Update on Simultaneous Topo-guided Photorefractive Keratectomy Immediately Followed by Corneal Collagen Cross-linking for Treatment of Progressive Keratoconus

Corneal collagen cross-linking (CXL) is a safe and effective technique for the management of corneal ecstatic disorders. It has been proven that CXL is effectual in stopping the progression of keratoconus quasi ‘freezing’ the cornea and in many cases avoiding corneal transplantation. Nevertheless, patients’ basic problem, which is the deterioration of their vision due to irregular astigmatism, remains. CXL combined with topography-guided photorefractive keratectomy (PRK) has been developed in order to achieve an important goal. To offer patients stability of their disorder and at the same time to assist them in achieving a functional vision by improving topographic outcomes. This article discusses update on this new combination therapy in the form of topo-guided PRK immediately followed by CXL as one-step procedure for treatment of progressive keratoconus.